Autism, Genetics and Spontaneous Mutation: New Findings Explained
Dr. Sebat explained that, while genetics clearly do play a role in autism, inherited genes are not always the key. In fact, according to studies at Cold Spring Harbor and elsewhere, a significant percentage of children with autism have new, spontaneous genetic mutations that are not found in their parents. In addition, these mutations vary from one another: so far, researchers have not found "the autism genes" or even the "autism mutation."
Why are these findings important? Sebat says that the finding could help parents determine whether a next child might be at high risk of being born with autism. If a child has a new, unique mutation that is not inherited, it's unlikely that the next child born of the same couple will have a similar mutation. He also feels that further, more focused research might lead to the discovery of genetic fingerprints for different types of autism - and thus to treatments that are specific to individual needs. Says Sebat, "Mutations hit genes AND the gene next door." So a child whose genetic differences encompass not only autistic symptoms but also gastrointestinal symptoms may have a completely different mutation from a child whose autism goes along with sleep issues. By pinpointing the mutation, researchers may be able to pinpoint the treatment.
Dr. Sebat stressed that there is, as yet, no proof of a connection between parental age and autism. "No genetic findings so far say that these genetic mutations come from older parents. To clarify: our paper on spontaneous mutations finds that in a percentage (about 15%) of kids, there is a new mutation - but all of the kids are different...a none came from their parents. [The mutations] could have occurred in sperm or egg, but wasn't something parents had in their own genome."
Comments
Has anyone else read a book entitled ‘Remote Viewing’ by Tim Riffat?
In his book he explains the history of mobile phone technology, where it began, the frequencies used, why they were used, and what can be caused by using different frequencies.
By transmitting a particular style of signal on a particular style of frequency - depression in an individual can be created. By transmitting a particular style of signal on a particular style of frequency - manic behaviour in a population can be created. Ultimately (and actually), the same frequencies can be used to control not only the behaviour of an individual (s), but also affect the DNA of individual(s) because of the effect the frequencies have on the human nervous system.
I firmly belive there will come a time when the epidemic of autism and mental health problems will be directly linked to the epidemic of mobile phone technology and the digital age. The human brain is nothing more than a very complicated series of electrical impulses - when those impulses are the subject of aggressive interference - what might the result be?
Let’s hope we all retain the mental faculties to answer the question!
We feel that we are giving our children ‘gifts’ when we give them mobile phones, digital this and that, in addition to internet, wi fi etc., I feel much better when I tell my son to play outside in the fresh air!
What was written in that article makes sense to me. However, there are some issues that can be noted if studies are done very carefully.
For example, in my husband’s family, his older brother’s wife developed a condition called “POLYHYDROAMNIOS”, excessive amniotic fluid during pregnancy w her first child. That child
had profound DD and died in neonatal period.
The same thing occurred to me, when I was pregnant w my son who has severe Autistic disorder (Infantile autism) and because of good prenatal care and post natal care, he survived, but w a DD for life.
There is something in the sperms of these two brothers. Polyhydroamnios, they say is a Mitochondrial thing for inheritance. I come from a different family and so did his brother’s wife. BUT both of us developed “POLYHYDROAMNIOS” syndrome and found out birth defects in neonates.
The mode of transmission seems to be from MIL most likely. We can’t chose the genome of our in-laws, but they can have an indirect or direct effect on our fetuses.
I just came to know about this when my BIL was visiting us and told about it after almost 17 yrs when I am thinking it must be from my side of the family! Not that it matters to me now, because we love our son dearly. We need LTC plan and support for him definitely.
LTC for 10 hours a day at home or outside our home for our kids is a must, esp after High School times, if you have a very difficult child w any DD. No provider will open up a program just only for your child.
So, think about this idea of LTC and visit me at
www.autismnet.com
to learn more about LTC, autism, etc.
Thanks.